Publications

  1. Tomoe Matagawa, Yukiko Sasazawa, Koki Agui, Motoki Fujimaki, Sayaka Kawano, Akihiro Ogura, Ken-ichi Takao, Masayuki Igarashi, and Siro Simizu,  “Antiproliferative activities through accelerating autophagic flux by basidalin and its analogs in human cancer cells”  Bioorg. Med. Chem. Lett. 2024, 104, 129713.
  2. Tomoki Uchida, Ryosuke Saito, Ken-ichi Takao, and Akihiro Ogura,  “Synthesis of Indoles via Sigmatropic Rearrangements and Olefin Isomerization”  Adv. Synth. Catal. 2024, 366, 465-472.
  3. Hiroki Yamamoto, Kohei Yamaoka, Ann Shinohara, Kouhei Shibata, Ken-ichi Takao, and Akihiro Ogura,  “Red-Light-Mediated Barton Decarboxylation Reaction and One-Pot Wavelength-Selective Transformations”  Chem. Sci. 2023, 14, 11243-11250.
  4. Rika Kawakami, Kohei Sato, Akihiro Ogura, Ken-ichi Takao, Yoshiki Iso, and Tetsuhiko Isobe,  “Open system synthesis of narrow-bandwidth red-fluorescent carbon quantum dots with a function of multi-metal ion sensing”  J. Mater. Chem. C 2023, 11, 4143-4152.
  5. Keiuke Yoshida, Arisa Hidaka, Yuri Fukami, Yuta Fujino, Yuri Imaizumi, Ken-ichi Takao, and Shinji Kitagaki,  “Development of TfOH-Catalyzed Spirocyclization by Intramolecular Friedel–Crafts-Type 1,4-Addition: Application to the Total Synthesis of the Unusual Proaporphine Alkaloid (±)-Misrametine”  Chem. Eur. J. 2022, 28, e202202188.
  6. Miho Oga, Yusei Takamatsu, Akihiro Ogura, and Ken-ichi Takao,  “Asymmetric Synthesis of Cyclopentene Compounds Containing All-Carbon Quaternary Stereocenters by (3 + 2) Cycloaddition and Its Application in the Formal Synthesis of (R)-(–)-Puraquinonic Acid”  J. Org. Chem. 2022, 87, 8788-8795.
  7. Junya Saegusa, Yoshiyuki Osada, Kazuki Miura, Yukiko Sasazawa, Akihiro Ogura, Ken-ichi Takao, and Siro Simizu,  “Elucidation of Structure-Activity Relationship of Humulanolides and Identification of Humulanolide Analog as a Nnovel HSP90 Inhibitor”  Bioorg. Med. Chem. Lett. 2022, 60, 128589.
  8. Kouhei Shibata, Ken-ichi Takao, and Akihiro Ogura,  “Diaryliodonium Salt-Based Synthesis of N-Alkoxyindolines and Further Insights into the Ishikawa Indole Synthesis”  J. Org. Chem. 2021, 86, 10067-10087.
  9. Akihiro Ogura, Taisuke Ito, Koujiro Moriya, Hiroki Horigome, and Ken-ichi Takao,  “Asymmetric Diels–Alder Reactions between Furans and Propiolates”  Tetrahedron Lett. 2021, 72, 153075.
  10. Taishu Yoshinaga, Momoka Shinoda, Yoshiki Iso, Tetsuhiko Isobe, Akihiro Ogura, and Ken-ichi Takao,  “Glycothermally Synthesized Carbon Dots with Narrow-Bandwidth and Color-Tunable Solvatochromic Fluorescence for Wide-Color-Gamut Displays”  ACS Omega 2021, 6, 1741-1750.
  11. Keisuke Yoshida, Hiroki Inoue, Yurika Oji, Hina Suzuki, and Ken-ichi Takao,  “Enantioselective Organocatalytic Construction of Spirochroman Derivative”  J. Org. Chem. 2020, 85, 10189-10197.
  12. Akihiro Ogura, Naoki Ichii, Kouhei Shibata, and Ken-ichi Takao,  “Red-Light-Mediated Barton-McCombie Reaction”  Bull. Chem. Soc. Jpn. 2020, 93, 936-941.
  13. Ken-ichi Takao, Akihiro Ogura, Keisuke Yoshida, and Siro Simizu,  “Total Synthesis of Natural Products Using Intramolecular Nozaki–Hiyama–Takai–Kishi Reactions”  Synlett 2020, 31, 421-433.
  14. Akihiro Sakama, Rika Kameshima, Yuko Motohashi, Wataru Sumida, Yuta Unno, Keisuke Yoshida, Akihiro Ogura, and Ken-ichi Takao,  “Stereoselective Synthesis of the Tricyclic Core of (–)-Callophycoic Acid A”  J. Org. Chem. 2020, 85, 3245-3264.
  15. Kazuki Miura, Wataru Matsuki, Akihiro Ogura, Ken-ichi Takao, and Siro Simizu,  “Identification of Vibsanin A Analog as a Novel HSP90 Inhibitor”  Bioorg. Med. Chem. 2020, 28, 115253.
  16. Ken-ichi Takao, Hirotaka Kai, Ai Yamada, Yuuki Fukushima, Daisuke Komatsu, Akihiro Ogura, and Keisuke Yoshida,  “Total Syntheses of (+)-Aquatolide and Related Humulanolides”  Angew. Chem. Int. Ed. 2019, 58, 9851-9855.
  17. Keisuke Otake, Kana Yamada, Kazuki Miura, Yukiko Sasazawa, So Miyazaki, Yuki Niwa, Akihiro Ogura, Ken-ichi Takao, and Siro Simizu,  “Identification of Topoisomerases as Molecular Targets of Cytosporolide C and Its Analog”  Bioorg. Med. Chem. 2019, 27, 3334-3338.
  18. Tatsuki Nakajima, Keita Takiguchi, Keisuke Yoshida, Akihiro Ogura, and Ken-ichi Takao,  “Studies toward the Synthesis of Perforatumone: Synthesis of the 7-Oxabicyclo[4.2.1]nonane-8,9-dione Core”  Heterocycles 2019, 99, 661-668.
  19. Keisuke Yoshida, Yuta Fujino, Yusei Takamatsu, Kohei Matsui, Akihiro Ogura, Yuri Fukami, Shinji Kitagaki, and Ken-ichi Takao,  “Enantioselective Total Synthesis of (-)-Misramine”  Org. Lett. 2018, 20, 5044-5047.
  20. Ken-ichi Takao, Kento Mori, Kenya Kasuga, Ryuki Nanamiya, Ayumi Namba, Yuuki Fukushima, Ryuichi Nemoto, Takuma Mogi, Hiroyuki Yasui, Akihiro Ogura, Keisuke Yoshida, and Kin-ichi Tadano,  “Total Synthesis of Clavilactones”  J. Org. Chem. 2018, 83, 7060-7075.
  21. Wataru Matsuki, So Miyazaki, Keisuke Yoshida, Akihiro Ogura, Yukiko Sasazawa, Ken-ichi Takao, and Siro Simizu,  “Synthesis and Evaluation of Biological Activities of Vibsanin A Analogs”  Bioorg. Med. Chem. Lett. 2017, 27, 4536-4539.
  22. Ken-ichi Takao, Ryuichi Nemoto, Kento Mori, Ayumi Namba, Keisuke Yoshida, and Akihiro Ogura,  “Total Synthesis and Structural Revision of Clavilactone D”  Chem. Eur. J. 2017, 23, 3828-3831.
  23. Keisuke Yoshida, Yohei Kanoko, and Ken-ichi Takao,  “Kinetically Controlled α-Selective O-Glycosylation of Phenol Derivatives Using 2-Nitroglycals by a Bifunctional Chiral Thiourea Catalyst”  Asian J. Org. Chem. 2016, 5, 1230-1236.
  24. Akihiro Sakama, Yoshiyasu Nishimura, Yuko Motohashi, Keisuke Yoshida, and Ken-ichi Takao,  “Stereoselective Construction of All-Carbon Quaternary Stereocenters by Allylboration of Chiral Aldehydes: Synthesis of a Fragment of (+)-Vibsanin A”  Tetrahedron 2016, 72, 5465-5471.
  25. Keisuke Yoshida, Hina Suzuki, Hiroki Inoue, Kohei Matsui, Yuta Fujino, Yohei Kanoko, Yukihiro Itatsu, and Ken-ichi Takao,  “Organocatalytic Regioselective Chlorosilylation of Oxirane Derivatives: Mild and Effective Insertion of Bulky Silyl Chloride by Using 4-Methoxypyridine N-Oxide”  Adv. Synth. Catal. 2016, 358, 1886-1891.
  26. Keisuke Yoshida, Yukihiro Itatsu, Yuta Fujino, Hiroki Inoue, and Ken-ichi Takao,  “Enantioselective Organocatalytic Construction of Spiroindane Derivatives by Intramolecular Friedel-Crafts-type 1,4-Addition”  Angew. Chem. Int. Ed. 2016, 55, 6734-6738.
  27. So Miyazaki, Yukiko Sasazawa, Takuma Mogi, Takehiro Suzuki, Keisuke Yoshida, Naoshi Dohmae, Ken-ichi Takao, and Siro Simizu,  “Identification of Seco-clavilactone B as a Small-molecule Actin Polymerization Inhibitor”  FEBS Lett. 2016, 590, 1163-1173.
  28. Keisuke Yoshida, Yuta Fujino, Yukihiro Itatsu, Hiroki Inoue, Yohei Kanoko, and Ken-ichi Takao,  “Amine-Free Silylation of Alcohols under 4-Methylpyridine N-Oxide-Catalyzed Conditions”  Tetrahedron Lett. 2016, 57, 627-631.
  29. Ken-ichi Takao, Shuji Noguchi, Shu Sakamoto, Mizuki Kimura, Keisuke Yoshida, and Kin-ichi Tadano,  “Total Synthesis of (+)-Cytosporolide A via a Biomimetic Hetero-Diels-Alder Reaction”  J. Am. Chem. Soc. 2015, 137, 15971-15977.
  30. Ken-ichi Takao, Kohei Tsunoda, Takuya Kurisu, Akihiro Sakama, Yoshiyasu Nishimura, Keisuke Yoshida, and Kin-ichi Tadano,  “Total Synthesis of (+)-Vibsanin A”  Org. Lett. 2015, 17, 756-759.
  31. Satoka Nagai, Yuka Yamagishi, Yuta Shimizu, Ken-ichi Takao, and Kin-ichi Tadano,  “An Access to the 13-Membered Cyclophane Substructure in GKK1032As: An Intramolecular 1,4-Addition Approach”  Heterocycles 2015, 90, 819-826.
  32. Keisuke Yoshida and Ken-ichi Takao,  “Catalytic Silylation of Secondary Alcohols by Pyridine N-Oxide Derivative”  Tetrahedron Lett. 2014, 55, 6861-6863.
  33. Ken-ichi Takao, Ryuki Nanamiya, Yuuki Fukushima, Ayumi Namba, Keisuke Yoshida, and Kin-ichi Tadano,  “Total Synthesis of (+)-Clavilactone A and (-)-Clavilactone B by Ring-Opening/Ring-Closing metathesis”  Org. Lett. 2013, 15, 5582-5585.
  34. Shu Sasaki, Suguru Samejima, Tomoki Uruga, Kai Anzai, Natsumi Nishi, Eriko Kawakita, Ken-ichi Takao, and Kin-ichi Tadano,  “Synthetic Studies of the Spirocyclic Cyclohexene Part of Versipelostatin, a Novel GRP78/Bip Molecular Chaperone Downregulator”  J. Antibiot. 2013, 66, 147-154.
  35. Ken-ichi Takao, Tomo Miyashita, Nozomi Akiyama, Takuya Kurisu, Kohei Tsunoda, and Kin-ichi Tadano,  “Construction of All-Carbon Quaternary Stereocenters by Zinc-Mediated Barbier-Type Allylation in Aqueous Media”  Heterocycles 2012, 86, 147-153.
  36. Ken-ichi Takao, Shu Sakamoto, Marianne Ayaka Touati, Yusuke Kusakawa, and Kin-ichi Tadano,  “Asymmetric Construction of All-Carbon Quaternary Stereocenters by Chiral-Auxiliary-Mediated Claisen Rearrangement and Total Synthesis of (+)-Bakuchiol”  Molecules 2012, 17, 13330-13344.
  37. Hayato Hosoi, Nobuyuki Kawai, Hideki Hagiwara, Takahiro Suzuki, Atsuo Nakazaki, Ken-ichi Takao, Kazuo Umezawa, and Susumu Kobayashi,  “Determination of the Absolute Structure of (+)-Akaterpin”  Chem. Pharm. Bull. 2012, 60, 137-143.
  38. Hayato Hosoi, Nobuyuki Kawai, Hideki Hagiwara, Takahiro Suzuki, Atsuo Nakazaki, Ken-ichi Takao, Kazuo Umezawa, and Susumu Kobayashi,  “Synthesis and Determination of the Relative Structure of Akaterpin, a Potent Inhibitor of PI-PLC”  Tetrahedron Lett. 2011, 52, 4961-4964.
  39. Daisuke Matsumura, Toshimasa Takarabe, Takumi Toda, Takashi Hayamizu, Kiyoto Sawamura, Ken-ichi Takao, and Kin-ichi Tadano, “Total Syntheses of (+)-Spiculoic Acid A and (+)-Zyggomphic Acid, New Marine Natural Products of Polyketide Origin”  Tetrahedron 2011, 67, 6730-6745.
  40. Ken-ichi Takao, Nobuhiko Hayakawa, Reo Yamada, Taro Yamaguchi, Hiroshi Saegusa, Masatoshi Uchida, Suguru Samejima, and Kin-ichi Tadano, “Total Syntheses of (+)- and (–)-Pestalotiopsin A”  J. Org. Chem. 2009, 74, 6452-6461. 
  41. Daisuke Matsumura, Takumi Toda, Takashi Hayamizu, Kiyoto Sawamura, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (+)-Spiculoic Acid A”  Tetrahedron Lett. 2009, 50, 3356-3358.
  42. Yoko Akashi, Ken-ichi Takao, and Kin-ichi Tadano, “Stereoselective α-Alkylation of Methyl 6-Deoxy-3,4-di-O-(tert-butyldimethylsilyl)-2-O-(2-methyl-3-oxobutanoyl)-α-D-glucopyranoside”  Tetrahedron Lett. 2009, 50, 1139-1142.
  43. Daisuke Yamashita, Yoshihisa Murata, Naotsuka Hikage, Ken-ichi Takao, Atsuo Nakazaki, and Susumu Kobayashi,  “Total Synthesis of (–)-Norzoanthamine”  Angew. Chem. Int. Ed. 2009, 48, 1404-1406.
  44. Ken-ichi Takao, Yuki Kojima, Tomo Miyashita, Kentaro Yashiro, Tatsuya Yamada, and Kin-ichi Tadano,  “Enantioselective Synthesis of a 3,5,5-Trialkylated Tetronic Acid Derivative”  Heterocycles 2009, 77, 167-172.
  45. Ken-ichi Takao, Nobuhiko Hayakawa, Reo Yamada, Taro Yamaguchi, Urara Morita, Soujiro Kawasaki, and Kin-ichi Tadano,  “Total Synthesis of (–)-Pestalotiopsin A”  Angew. Chem. Int. Ed. 2008, 47, 3426-3429.
  46. Hiroto Kubo, Ikuko Kozawa, Ken-ichi Takao, and Kin-ichi Tadano  “Stereoselective Synthesis of Highly Enantioenriched 3-Methyl-2-cyclohexen-1-ones Possessing an Asymmetric Quaternary Carbon as C-4 or C-6: A Sugar Template Approach”  Tetrahedron Lett. 2008, 49, 1203-1207.
  47. Toshimi Anzo, Akari Suzuki, Kiyoto Sawamura, Toru Motozaki, Madoka Hatta, Ken-ichi Takao, and Kin-ichi Tadano  “Formal Synthesis of Tubelactomicins via a Transannular Diels–Alder Approach”  Tetrahedron Lett. 2007, 48, 8442-8448.
  48. Kiyoto Sawamura, Keigo Yoshida, Akari Suzuki, Toru Motozaki, Ikuko Kozawa, Takashi Hayamizu, Ryosuke Munakata, Ken-ichi Takao, and Kin-ichi Tadano  “Total Syntheses of Natural Tubelactomicins B, D, and E: Establishment of Their Stereochemistries” J. Org. Chem. 2007, 72, 6143-6148.
  49. Daisuke Sasaki, Daisuke Sawamoto, Ken-ichi Takao, Kin-ichi Tadano, Masayuki Okue, and Kei-ichi Ajito  “Stereoselective Mannich-like Reactions of Ester Enolates Generated on Sugar-Templates: A Novel Access to A Key Intermediate for 1β-Methyl Carbapenem Synthesis”  Heterocycles 2007, 72, 103-110.
  50. Ikuko Kozawa, Yoko Akashi, Kumiko Takiguchi, Daisuke Sasaki, Daisuke Sawamoto, Ken-ichi Takao, and Kin-ichi Tadano  “Stereoselective Double Alkylation of the Acetoacetate Ester α-Carbon on a D-Glucose-Derived Template: Application to the Synthesis of Enantiopure Cycloalkenones Bearing an Asymmetric Quaternary Carbon”  Synlett 2007, 399-402.
  51. Hiroyuki Yasui, Shun Yamamoto, Ken-ichi Takao, and Kin-ichi Tadano  “Synthetic Studies Toward Clavilactone A: A Concise Access to α,γ-Substituted γ-Butenolides by Metathesis”  Heterocycles 2006, 70, 135-141.
  52. Shi-ya, Aoki, Taro Tsukude, Yukari Miyazaki, Ken-ichi Takao, and Kin-ichi Tadano  “Total Synthesis of (–)-Pramanicin”  Heterocycles 2006, 69, 49-54.
  53. Hiroyuki Yasui, Kunihiro Hirai, Shun Yamamoto, Ken-ichi Takao, and Kin-ichi Tadano  “Total Syntheses of (+)-1893B and Its Three Diastereomers and Evaluation of Their Biological Activities”  J. Antibiot. 2006, 59, 456-463.
  54. Hiroyuki Yasui, Kunihiro Hirai, Shun Yamamoto, Ken-ichi Takao, and Kin-ichi Tadano  “Total Synthesis of (+)-1893B Aimed at Establishing Its Stereochemistry”  Heterocycles 2006, 67, 123-128.
  55. Ken-ichi Takao, Hiroshi Saegusa, Tomohiro Tsujita, Takenori Washizawa, and Kin-ichi Tadano  “Synthetic Studies of Pestalotiopsin A: Asymmetric Synthesis of the 2-Oxabicyclo[3.2.0]heptane Substructure”  Tetrahedron Lett. 2005, 46, 5815-5818.
  56. Toru Motozaki, Kiyoto Sawamura, Akari Suzuki, Keigo Yoshida, Tatsuo Ueki, Aiko Ohara, Ryosuke Munakata, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (+)-Tubelactomicin A. 2.  Synthesis of the Upper-Half Segment and Completion of the Total Synthesis”  Org. Lett. 2005, 7, 2265-2267.
  57. Toru Motozaki, Kiyoto Sawamura, Akari Suzuki, Keigo Yoshida, Tatsuo Ueki, Aiko Ohara, Ryosuke Munakata, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (+)-Tubelactomicin A. 1.  Stereoselective Synthesis of the Lower-Half Segment by an Intramolecular Diels–Alder Approach”  Org. Lett. 2005, 7, 2261-2264.
  58. Ken-ichi Takao, Hiroyuki Yasui, Shun Yamamoto, Daisuke Sasaki, Soujiro Kawasaki, Gohshi Watanabe, and Kin-ichi Tadano,  “Asymmetric Total Syntheses of (+)-Mycoepoxydiene and Related Natural Product (–)-1893A: Application of One-Pot Ring-Opening/Cross/Ring-Closing Metathesis to Construct their 9-Oxabicyclo[4.2.1]nona-2,4-diene Skeleton”  J. Org. Chem. 2004, 69, 8789-8795.
  59. Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Sugar as a Tool for Asymmetric Synthesis: Some Effective Approaches”  Synlett 2004, 2066-2080.
  60. Shin-ya Aoki, Takahiro Oi, Kazuya Shimizu, Ryota Shiraki, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Syntheses of Natural Pseurotins A, F2, and Azaspirene”  Bull. Chem. Soc. Jpn. 2004, 77, 1703-1716.
  61. Ryosuke Munakata, Hironori Katakai, Tatsuo Ueki, Jun Kurosaka, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of Macquarimicins Using an Intramolecular Diels–Alder Approach Inspired by a Biosynthetic Pathway”  J. Am. Chem. Soc. 2004, 126, 11254-11267.
  62. Shin-ya Aoki, Takahiro Oi, Kazuya Shimizu, Ryota Shiraki, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Syntheses of Natural Pseurotins A and F2 and Azaspirene”  Heterocycles 2004, 62, 161-166.
  63. Ryosuke Munakata, Hironori Katakai, Tatsuo Ueki, Jun Kurosaka, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (+)-Macquarimicin A”  J. Am. Chem. Soc. 2003, 125, 14722-14723.
  64. Kouji Kuramochi, Seigo Nagata, Hideyoshi Itaya, Yasuaki Matsubara, Takashi Sunoki, Hiromi Uchiro, Ken-ichi Takao, and Susumu Kobayashi,  “A Convergent Total Synthesis of Epolactaene: an Application of the Bridgehead Oxiranyl Anion Strategy”  Tetrahedron 2003, 59, 9743-9758.
  65. Shingo Asano, Testuo Tamai, Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Stereoselective 1,4-Addition of the Enolate Generated from 6-Deoxy-D-Glucopyranoside-Derived Propionyl Ester to Methyl Crotonate: Application to Total Synthesis of (–)-Lasiol”  Synlett 2003, 2252-2254.
  66. Testuo Tamai, Shingo Asano, Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Stereoselective [3+2] Cycloadditions of Nitrile Oxides to Methyl 4-O-Acryloyl-6-deoxy-2,3-O-(t-butyldimethylsilyl)-α-D-glucopyranoside”  Synlett 2003, 1865-1867.
  67. Sara Richter, Barbara Gatto, Daniele Fabris, Ken-ichi Takao, Susumu Kobayashi, and Manlio Palumbo,  “Clerocidin Alkylates DNA through its Epoxide Function: Evidence for a Fine Tuned Mechanism of Action”  Nucleic Acids Res. 2003, 31, 5149-5156.
  68. Shin-ya Aoki, Takahiro Ohi, Kazuya Shimizu, Ryota Shiraki, Ken-ichi Takao, and Kin-ichi Tadano,  “Stereocontrolled Synthesis of a Highly Functionalized 1,7-Dioxaspiro[4.4]nonane Derivative Related to Antibiotic Pseurotins”  Heterocycles 2002, 58, 57-61.
  69. Ken-ichi Takao, Tomohiro Tsujita, Manabu Hara, and Kin-ichi Tadano,  “Asymmetric Total Syntheses of (+)-Cheimonophyllon E and (+)-Cheimonophyllal” J. Org. Chem. 2002, 67, 6690-6698.
  70. Ken-ichi Takao, Gohshi Watanabe, Hiroyuki Yasui, and Kin-ichi Tadano,  “Total Synthesis of (±)-Mycoepoxydiene, a Novel Fungal Metabolite Having an Oxygen-Bridged Cyclooctadiene Skeleton”  Org. Lett. 2002, 4, 2941-2943.
  71. Takayuki Nagatsuka, Shuhei Yamaguchi, Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Diastereoselective Diels–Alder Reactions of Acrylic Esters Incorporated into a Variety of Hexopyranosides” J. Carbohydr. Chem. 2001, 20, 519-535.
  72. Ken-ichi Takao, Tomoko Sasaki, Tomohito Kozaki, Yumiko Yanagisawa, Kin-ichi Tadano, Akira Kawashima, and Hideki Shinonaga,  “Syntheses and Absolute Stereochemistries of UPA0043 and UPA0044, Cytotoxic Antibiotics Having a p-Quinone-methide Structure”  Org. Lett. 2001, 3, 4291-4294.
  73. Kiichiro Totani, Shingo Asano, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Stereoselective α-Alkylations, 1,4-Additions, and One-pot 1,4-Addition/α-Methylations Achieved on 4-O-Acyl and 4-O-Crotonyl Derivatives of Methyl 6-Deoxy-2,3-di-O-(t-butyldimethylsilyl)-α-D-glucopyranoside”  Synlett 2001, 1772-1776.
  74. Ryosuke Munakata, Tatsuo Ueki, Hironori Katakai, Ken-ichi Takao, and Kin-ichi Tadano,  “Synthetic Study of Macquarimicins: Highly Stereoselective Construction of the AB-Ring System”  Org. Lett. 2001, 3, 3029-3032.
  75. Kiichiro Totani, Takayuki Nagatsuka, Shuhei Yamaguchi, Ken-ichi Takao, Shigeru Ohba, and Kin-ichi Tadano,  “Highly Diastereoselective 1,4-Addition of an Organocuprate to Methyl α-D-Gluco, α-D-Manno-, or α-D-Galactopyranosides Tethering an α,β-Unsaturated Ester.  Novel Asymmetric Access to β-C-Substituted Butanoic Acids”  J. Org. Chem. 2001, 66, 5965-5975.
  76. Kimiko Makino, Yohei Fujita, Ken-ichi Takao, Susumu Kobayashi, and Hiroyuki Ohshima,  “Preparation and Properties of Thermosensitive Hydrogel Microcapsules”  Colloids Surf. B 2001, 21, 259-263.
  77. Yoshikazu Suzuki, Aiko Ohara, Kenji Sugaya, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (–)-Mniopetal F, a Novel Inhibitor of RNA-directed DNA-polymerases”  Tetrahedron 2001, 57, 7291-7301.
  78. Ken-ichi Takao, Manabu Hara, Tomohiro Tsujita, Ken-ichi Yoshida, and Kin-ichi Tadano,  “Total Synthesis of (+)-Cheimonophyllon E, a Bisabolane Sesquiterpenoid”  Tetrahedron Lett. 2001, 42, 4665-4668.
  79. Takayuki Nagatsuka, Shuhei Yamaguchi, Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Stereoselective Diels–Alder Reactions Achieved on Some Hexopyranosidic Templates”  Synlett 2001, 481-484.
  80. Ken-ichi Takao, Hiroshi Saegusa, and Kin-ichi Tadano,  “Orthoester Claisen Rearrangement of a D-Glucose-derived Spirocyclic Substrate”  J. Carbohydr. Chem. 2001, 20, 57-69.
  81. Yoshikazu Suzuki, Ryoko Nishimaki, Makoto Ishikawa, Takeshi Murata, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (–)-Mniopetal E, a Novel Biologically Intriguing Drimane Sesquiterpenoid”  J. Org. Chem. 2000, 65, 8595-8607.
  82. Nobuyuki Kawai, Yoko Fujibayashi, Seiya Kuwabara, Ken-ichi Takao, Yasuharu Ijuin, and Susumu Kobayashi,  “Synthesis of a Potential Key Intermediate of Akaterpin, Specific Inhibitor of PI-PLC”  Tetrahedron 2000, 56, 6467-6478.
  83. Naotsuka Hikage, Hironori Furukawa, Ken-ichi Takao, and Susumu Kobayashi,  “Synthetic Studies of Zoanthamine/Norzoanthamine:  Biogenetic-like One-Step Construction of the Heterocyclic Aminal Core (CDEFG Ring) from a Monocyclic Precursor”  Chem. Pharm. Bull. 2000, 48, 1370-1372.
  84. Ryosuke Munakata, Kiichiro Totani, Ken-ichi Takao, and Kin-ichi Tadano,  “Highly Stereoselective Lewis Acid Mediated Conjugate Radical Additions to Methyl α-D-Glucopyranoside Derivatives Tethering an Unsaturated Ester Moiety at C-4”  Synlett 2000, 979-982.
  85. Eiju Suzuki, Ken-ichi Takao, and Kin-ichi Tadano,  “Synthesis of an Enantiomeric 2,5-Di-(E)-propenyltetrahydrofuran-3,4-diol Derivative”  Heterocycles 2000, 52, 519-523.
  86. Ken-ichi Takao, Hiroshi Saegusa, Gohshi Watanabe, and Kin-ichi Tadano,  “Stereoselective Carbon–carbon Bond Forming Reaction of Chiral Cyclopent-2-enone and Cyclopentene-1-methanol, both Spiro-connecting a 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranosyl Ring”  Tetrahedron: Asymmetry 2000, 11, 453-464.
  87. Kiichiro Totani, Takayuki Nagatsuka, Ken-ichi Takao, Shigeru Ohba, and Kin-ichi Tadano,  “Highly Stereoselective 1,4-Conjugate Addition of Organocopper Reagents to Methyl α-D-Glucopyranoside Derivatives Tethering an Unsaturated Ester Moiety at C-4 or C-6”  Org. Lett. 1999, 1, 1447-1450.
  88. Yoshikazu Suzuki, Ryoko Nishimaki, Makoto Ishikawa, Takeshi Murata, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of (–)-Mniopetal E, a Novel Biologically Intriguing Drimane Sesquiterpenoid”  Tetrahedron Lett. 1999, 40, 7835-7838.
  89. Kouji Kuramochi, Seigo Nagata, Hideyoshi Itaya, Ken-ichi Takao, and Susumu Kobayashi,  “Convergent Total Synthesis of Epolactaene:  Application of Bridgehead Oxiranyl Anion Strategy”  Tetrahedron Lett. 1999, 40, 7371-7374.
  90. Kouji Kuramochi, Hideyoshi Itaya, Seigo Nagata, Ken-ichi Takao, and Susumu Kobayashi,  “Generation and Reaction of an Oxiranyl Anion Derived from α,β-Epoxy-γ-butyrolactone”  Tetrahedron Lett. 1999, 40, 7367-7370.
  91. Nobuyuki Kawai, Ken-ichi Takao, and Susumu Kobayashi,  “Synthetic Study of Akaterpin:  Determination of the Relative Stereochemistry of the Upper Decalin Moiety with Disulfated Hydroquinon”  Tetrahedron Lett. 1999, 40, 4193-4196.
  92. Naganori Numao, Yukiko Hirota, Akiyo Iwahori, Shun-ichi Kidokoro, Masanori Sasatsu, Isamu Kondo, Sachiko Itoh, Etsuko Itoh, Tadashi Katoh, Noriko Shimozono, Akiko Yamazaki, Ken-ichi Takao, and Susumu Kobayashi,  “Biological Activities of 1,1,6-Trisubstituted Indanes:  Beyond Magainin 2”  Biol. Pharm. Bull. 1999, 22, 73-75.
  93. Naotsuka Hikage, Hironori Furukawa, Ken-ichi Takao, and Susumu Kobayashi,  “Synthetic Studies of Zoanthamine/Norzoanthamine Alkaloids:  Construction of the Heterocyclic Aminal Core (CDEFG Ring)”  Tetrahedron Lett. 1998, 39, 6241-6244.
  94. Naotsuka Hikage, Hironori Furukawa, Ken-ichi Takao, and Susumu Kobayashi,  “Synthetic Studies of Zoanthamine/Norzoanthamine Alkaloids:  Advanced Intermediate for the Heterocyclic Aminal Core”  Tetrahedron Lett. 1998, 39, 6237-6240.
  95. Hironori Furukawa, Kazunori Koide, Ken-ichi Takao, and Susumu Kobayashi,  “Glycosyl 2-Pyridinecarboxylate as an Effective Glycosyl Donor:  Glycosidation of Mannose, 2-Azidosugar, and 2-Deoxysugar into Disaccharides”  Chem. Pharm. Bull. 1998, 46, 1244-1247.
  96. Ken-ichi Takao, Seigo Nagata, Susumu Kobayashi, Hisanaka Ito, and Takeo Taguchi,  “Model Study for the Total Synthesis of Antifungal Australifungin:  Construction of α-Diketone and β-Ketoaldehyde Moieties”  Chem. Lett. 1998, 447-448.
  97. Hisanaka Ito, Miyoko Matsumoto, Takeshi Yoshizawa, Ken-ichi Takao, and Susumu Kobayashi,  “Structurally Simplified Zaragozic Acid (Squalestatin):  Stereoselective Preparation of a 3,4-Unsubstituted Derivative”  Tetrahedron Lett. 1997, 38, 9009-9012.
  98. Naganori Numao, Yukiko Hirota, Akiyo Iwahori, Masanori Sasatsu, Isamu Kondo, Ken-ichi Takao, and Susumu Kobayashi,  “Antibacteral Activity of (±)-6-Benzyl-1-(3-carboxypropyl)-indane;  A Possible Way to Identify Leading Novel Anti-H. pylori Agents”  Biol. Pharm. Bull. 1997, 20, 1204-1207.
  99. Ken-ichi Takao and Susumu Kobayashi,  “Synthetic Study on Antitumor Antibiotic Terpentecin:  Construction of the Carbobicyclic Decalin Moiety”  Tetrahedron Lett. 1997, 38, 6685-6688.
  100. Tetsuta Oshitari, Masakatsu Shibasaki, Takeshi Yoshizawa, Ken-ichi Takao, and Susumu Kobayashi, “Synthesis of 2-O-(3-O-Carbamoyl-α-D-mannopyranosyl)-L-gulopyranose: Sugar Moiety of Antitumor Antibiotic Bleomycin”  Tetrahedron 1997, 53, 10993-11006.
  101. Ken-ichi Takao, Yasuyuki Aiba, Hisanaka Ito, and Susumu Kobayashi,  “Stereoselective Route to the Highly Oxidated Sidechain Moiety of Terpentecin and Related Antibiotics”  Chem. Lett. 1996, 931-932.
  102. Hisanaka Ito, Nobuyuki Imai, Ken-ichi Takao, and Susumu Kobayashi,  “Enantioselective Synthesis of Curacin A. 2.  Total Synthesis of Curacin A by Condensation of C1-C7, C8-C17, and C18-C22 Segments”  Tetrahedron Lett. 1996, 37, 1799-1800.
  103. Ken-ichi Takao, Hiroshi Ochiai, Ken-ichi Yoshida, Takahiko Hashizuka, Hirokazu Koshimura, Kin-ichi Tadano, and Seiichiro Ogawa,  “Novel Total Synthesis of (+)-Eremantholide A”  J. Org. Chem. 1995, 60, 8179-8193.
  104. Ken-ichi Takao, Hiroshi Ochiai, Takahiko Hashizuka, Hirokazu Koshimura, Kin-ichi Tadano, and Seiichiro Ogawa,  “A Total Synthesis of (+)-Eremantholide A”  Tetrahedron Lett. 1995, 36, 1487-1490.
  105. Ken-ichi Takao, Yuya Nigawara, Emiko Nishino, Izumi Takagi, Koji Maeda, Kin-ichi Tadano, and Seiichiro Ogawa,  “Stereoselective Total Syntheses of (–)-Desoxoprosopinine and (–)-Desoxoprosophylline: Palladium(0)-Catalyzed Intramolecular N-Alkylation for the Key Piperidine Ring Formation”  Tetrahedron 1994, 50, 5681-5704.
  106. Kin-ichi Tadano, Ken-ichi Takao, Yuya Nigawara, Emiko Nishino, Izumi Takagi, Koji Maeda, and Seiichiro Ogawa,  “Stereoselective Total Syntheses of (–)-Desoxoprosopinine and (–)-Desoxoprosophylline: Palladium(0)-Catalyzed Intramolecular N-Alkylation for the Key Piperidine Ring Formation”  Synlett 1993, 565-567.
  107. Kin-ichi Tadano, Satoshi Kanazawa, Ken-ichi Takao, and Seiichiro Ogawa,  “Intramolecular Aldol Condensation Applied to D-Glucose-derived δ-Ketoaldehydes” Tetrahedron 1992, 48, 4283-4300.

 Reviews

  1. Akihiro Sakama, Akihiro Ogura, Keisuke Yoshida, and Ken-ichi Takao,  “The Stereoselective Construction of All-Carbon Quaternary Stereocenters by Allylations and Its Application to Synthetic Studies of Natural Products”  J. Synth. Org. Chem., Jpn. 2020, 78, 1039-1047.
  2. Akihiro Ogura and Ken-ichi Takao,  “Recent Advances in the Total Synthesis of Clavilactones”  Heterocycles 2020, 100, 1355-1370.
  3. Ken-ichi Takao and Kin-ichi Tadano,  “Recent Advances in the Synthetic Studies of Pestalotiopsin A and Related Caryophyllene-Type Sesquiterpenoids”  In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier: Amsterdam, 2013; Vol. 39, pp 161-187.
  4. Ken-ichi Takao and Kin-ichi Tadano,  “Synthesis of Nitrogen- and Oxygen-Bridged Seven- to Ten-Membered Carbocycles Using Metathesis Reactions”  Heterocycles 2010, 81, 1603-1629.
  5. Ken-ichi Takao, Ryosuke Munakata, and Kin-ichi Tadano,  “Recent Advances in Natural Product Synthesis by Using Intramolecular Diels–Alder Reactions”  Chem. Rev. 2005, 105, 4779-4807.
  6. Yoshikazu Suzuki, Ken-ichi Takao, and Kin-ichi Tadano,  “Total Synthesis of Biologically Intriguing Drimane-Type Sesquiterpenoids via Intramolecular Diels–Alder Approaches”  In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier: Amsterdam, 2003; Vol. 29, pp 127-167.
  7. Ken-ichi Takao, Jun Ishihara, and Kin-ichi Tadano,  “Total Syntheses of (+)-Eremantholide A and (–)-Verrucarol: From D-Glucose to Biologically Intriguing Sesquiterpenes”  In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier: Amsterdam, 2000; Vol. 24, pp 3-51.