Takaaki Sato (Ph.D)


E-mail : takaakis@applc.keio.ac.jp

Associate Professor
Department of Applied Chemistry
Faculty of Science and Technology
Keio University

【Education】
<Undergraduate>
Tohoku University, Sendai, Japan
April 1997 - March 2001
Advisor: Prof. Masahiro Hirama

<Graduate>
Tohoku University, Sendai, Japan
Ph.D., March 2006
Advisor: Prof. Masahiro Hirama

<Postdoctoral>
University of California, Irvine, USA
April 2006 - March 2008
Advisor: Prof. Larry E. Overman


【Professional Positions】
April 2005-March 2007: JSPS fellows (DC2)
April 2008-March 2012: Assistant Professor, Keio University, Department of Applied Chemistry
April 2012-March 2016: Lecturer, Keio University, Department of Applied Chemistry
April 2016-present: Associate Professor, Keio University, Department of Applied Chemistry 



【Research Projects】
1. Functionalization of Amides and Application to Total Synthesis

2. Synthesis of Skipped Dienes and Application to Total Synthesis


【Representative Publications】
(1) Shirokane, K.; Kurosaki, Y.; *Sato, T.; *Chida, N. , .
  "A Directed Entry to Substituted N-Methoxyamines from N-Methoxyamides
   via N-Oxyiminium Ions"
  
Angew. Chem. Int. Ed. 2010, 49, 6369-6372

  This article was highlighted in SYNFACT, 2010, 6, 1412.

(2) Shirokane, K.; Wada, T.; Yoritate, M.; Minamikawa, R.; Takayama, N; *Sato, T.; *Chida, N. ,
  "Total Synthesis of (±)-Gephyrotoxin by Amide-Selective Reductive Nucleophilic Additon"
  Angew. Chem. Int. Ed. 2014, 53, 512-516.

  This article was selected as VIP (Very Important Paper).
  This article was selected as the most accessed articles in ACIE in 12/2013.
  This article was selected as the most accessed articles in ACIE in 11/2013-10/2014
  This article was highlighted in SYNFACT 2014,10, 116.

(3) Yoritate, M.; Meguro, T.; Matsuo, N.; Shirokane, K.; *Sato, T.; Chida, N.
  "Two-step Synthesis of Multi-substituted Amines by Using an N-methoxy Group
  as a Reactivity Control Element"
  Chem. Eur. J. 2014, 20, 8210-8216.

  This article was selected as VIP (Very Important Paper).
  This article was selected as a front cover.

(4) Katahara, S.; Kobayashi, S.; Fujita, K.; Matsumoto. T.; *Sato, T.; *Chida, N.
  "An Iridium-Catalyzed Reductive Approach to Nitrones from N-Hydroxyamides"
  J. Am. Chem. Soc.
2016,138, 5246-5249.

(5) Suto, T..; Yanagita, Y.; Nagashima, Y. Takikawa, S.; Kurosu, Y; Matsuo, N. *Sato, T.; *Chida, N.
  "Unified Total Synthesis of Madangamines A, C, and E",
  J. Am. Chem. Soc.
2017, 2952-2955.

  This article was selected as the most read articles on a monthly basis
  This article was highlighted in SYNFACT 2017,13, 450.

(6) Makoto Y.; Takahashi, Y.; Tajima, H.; Ogihara, C.; Yokoyama, T.; Soda, Y.; Oishi, T.;
  *Sato, T.; *Chida, N.

  "Unified Total Synthesis of Stemoamide-Type Alkaloids

   by Chemoselective Assembly of Five-Membered Building Blocks"
  J. Am. Chem. Soc. 2017, 139, accepted.



Publication List (PDF)


【Awards】
1. CSJ Student Presentation Award 2005 (2005)

2. The Otsuka Pharmaceutical Co. Award in Synthetic Organic Chemistry, Japan (2009)

3. Young Scientist's Research Award in Natural Product Chemistry (2014)

4. BCSJ award

 "Total Synthesis of (±)-Gephyrooxin and (±)-Perhydroggephyrotoxin" (2015)

 "Reductive Approache to Nitrones from N-Siloxyamides and N-Hydroxyamides" (2017)


5. Incentive Award in Synthetic Organic Chemistry, Japan (2017)


6. International Symposium on Pure & Applied Chemistry 2017, Lecture Award (2017)
 ”Unified Total Synthesis of Stemoamide-Type Alkaloids”