Laboratory for Analytical Chemistry

Citterio Laboratory


Innovation of Chemical Sensors

Keio University

Faculty of Science and Technology

Department of Applied Chemistry

Sensing Devices


Our research group has a long history in the development of (bio)chemical sensing devices both based on optical (e.g. ion-selective optodes) and on electrochemical (e.g. ion-selective electrodes) transduction. A variety of functional molecules have been developed for these purposes including highly selective ion recognizing compounds (ionophores, chromoionophores, fluoroionophores).


In order to convert these molecular probes into reversibly working sensing devices, they have been immobilized to manifold matrices including PVC and other polymeric membranes, glass surfaces, paper and mesoporous silica films.


An example of a simple sensing device that has become commercially available is a test paper impregnated with a colorimetric indicator for the detection of formaldehyde in indoor air ("Dr. Sickhouse").


A more recent example is a glass pH-optode with fluorescence readout, characterized by highly stable optical signals, suitable for longterm monitoring of pH values.


For specific information, please refer to our list of publications.



Citterio Laboratory 2019

Last update: January 12, 2019